In a large mixing bowl, whisk together the flour, sugar, salt, and instant yeast until well combined.
In a separate bowl, mix the warm milk, melted butter, egg, and vanilla extract until fully blended.
Pour the wet ingredients into the dry ingredients and stir with a wooden spoon or spatula until a sticky dough forms and no dry flour remains.
Cover the bowl tightly with plastic wrap or a clean kitchen towel and let the dough rise at room temperature for 1 hour 30 minutes, or until doubled in size.
Preheat the oven to 375°F (190°C). Lightly grease a 9×5 inch loaf pan.
Gently transfer the dough into the prepared loaf pan, smoothing the top with a spatula.
Bake the bread in the preheated oven for 35 to 40 minutes, or until the top is golden brown and a toothpick inserted into the center comes out clean.
Remove the bread from the oven and let it cool in the pan for 10 minutes.
Transfer the bread to a wire rack and allow it to cool completely before slicing.